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Search Results for " growth hormone releasing hormone "

Targets Recommended: GHSR

25

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1155L	Human growth hormone-releasing factor acetate	GHSR	GPCR/G Protein
	Human growth hormone-releasing factor acetate 是一种下丘脑多肽，通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。
TP1155	Human growth hormone-releasing factor Growth Hormone Releasing Factor human
	Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothalamus. The main role of growth hormo
T82322	GHRF, mouse Mouse growth hormone-releasing factor
	GHRF, mouse为含44个氨基酸的小鼠生长激素释放肽，能够促进生长激素的释放与合成。
T75713	Human growth hormone-releasing factor TFA
	Growth Hormone Releasing Factor human TFA 是下丘脑多肽，通过与GHRHR结合，刺激生长激素生成和释放。
TP2328L	CJC-1295 acetate(863288-34-0 free base) DAC:GRF acetate	GHSR	GPCR/G Protein
	CJC-1295 acetate(863288-34-0 free base) (DAC:GRF acetate) 是生长激素释放激素 (GHRH)（也称为生长激素释放因子 (GRF)）和生长激素促分泌素 (GHS) 的合成类似物。
TP2236L	Cortistatin-8 acetate Cortistatin-8 acetate(485803-62-1 Free base)	GHSR	GPCR/G Protein
	Cortistatin-8 acetate 是一种皮质抑素类似物，是一种GHS-R拮抗剂，对生长激素促分泌素受体有抑制作用。Cortistatin-8 acetate 是一种合成皮质抑素衍生的生长素释放肽受体配体，不会改变人类对酰化生长素释放肽或海沙瑞林的内分泌反应。
T34281	Relamorelin BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131	GHSR	GPCR/G Protein
	Relamorelin (RM-131)是一种具有选择性和有效性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂，是一种有效的生长素释放肽模拟物，对 GHS-1a 受体具有很高的亲和力。Relamorelin 是一种具有中枢渗透性的五肽，可增加生长激素水平，加速胃排空，具有研究恶病质的潜力。
T7809L	Ipamorelin 2 Pivalic acid NNC-26-0161	Others	Others
	Ipamorelin 2 Pivalic acid (NNC-26-0161) 是一种生长激素释放肽，可诱导大鼠纵向骨生长。
T3630	Relugolix RVT-601,瑞卢戈利,TAK-385	GNRH Receptor	GPCR/G Protein
	Relugolix (RVT-601) 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比，它对人和猴子的受体具有高亲和力和强拮抗活性，它们的 IC50值分别为0.33 nM 和0.32 nM。它可用于研究性激素依赖性疾病，如子宫肌瘤、子宫内膜异位症、前列腺癌等。
TP1570	Cortistatin-14	Somatostatin	GPCR/G Protein
	Cortistatin-14 是一种与生长抑素-14结构相似的神经肽，具有抗惊厥和神经保护作用，通过激活 sst（2）、生长素释放肽和 GABA（A/B）受体损害小鼠的识别记忆巩固，可用于研究脓毒症引发的认知障碍。
T5025L2	Pralmorelin HCl WAY-GPA 748,WAY-GPA-748 WAY-GPA748,Pralmorelin dihydrochloride
	Pralmorelin HCl is regarded as a Growth Hormone Releasing Factor.
T76317	[His1,Nle27] GHRF (1-32), amide, human
	[His1,Nle27] GHRF (1-32), amide, human为一种生长激素释放激素（GHRH）类似物，对GHRHR受体具有较好的亲和力。
T36377	Somatorelin (1-44) amide (human) (trifluoroacetate salt)
	Somatorelin (1-44) amide is a synthetic peptide that corresponds to the full 44-amino acid sequence of growth hormone-releasing hormone (GHRH), a hormone that stimulates the production of growth hormone from the pituitary gland and is involved in the regulation of cell proliferation and differentiation.1,2Somatorelin induces growth hormone release similarly to GHRHin vitroandin vivo.1
T76318	GHRF, porcine
	GHRF, porcine 是一种生长激素释放激素 (GHRH) 多肽 (porcine)。GHRF, porcine 与 GHRHR 受体结合并促进生长激素的释放。
T7809	Ipamorelin 伊帕瑞林,NNC-26-0161	Others	Others
	Ipamorelin (NNC-26-0161) 是一种生长激素释放肽，可诱导大鼠纵向骨生长。
T83549	(D-Ala2)-GRF (1-29) amide (human)
	'(D-Ala2)-GRF (1-29) amide (human)' 为一种GRF的超激动剂，其GH释放活性在猪和大鼠体内极为显著，大约为GRF (1-29)活性的50倍。
T76204	a-Helical Corticotropin Releasing Factor (9-41)
	α-Helical Corticotropin Releasing Factor (9-41) 为corticotropin releasing factor (CRF)的拮抗剂，具有降低体内血浆生长激素(GH)水平的功能。
T76312L	sGnRH-A acetate
	sGnRH-A醋酸盐是一种鲑鱼促性腺激素释放激素(GnRH)类似物。它能促进生长激素的分泌，并用作人工授精时的排卵诱导剂。
T76312	sGnRH-A
	sGnRH-A，一种鲑鱼促性腺激素释放激素(GnRH)类似物，能够促进生长激素的分泌，并作为人工授精中的排卵诱导剂使用。
T78039	Acetyl-(D-Arg2)-GRF (1-29) amide (human)
	Acetyl-(D-Arg2)-GRF (1-29) amide (human) 是一种针对人体的生长激素释放因子(GRF)拮抗剂，其主要作用是抑制生长激素(GH)的释放，广泛应用于内分泌学领域的研究。
T82000	JV-1-36
	"JV-1-36是一种GHRH拮抗剂，能够抑制A549肺癌细胞的活性氧生成，适用于研究GHRH拮抗剂的体外作用。"
T78023	MR 409
	MR 409是一种选择性的生长激素释放激素(GHRH)激动剂，能够显著增强脑缺血小鼠内源性神经发生，具有神经保护作用，并可抑制肺癌的体内生长。
T76325	GHRF, bovine
	GHRF, bovine (bGRF(1-44)-NH2) 是牛生长激素 (GH) 释放因子 (GHRF)。GHRF, bovine 促牛生长激素释放，并受到Hydrocortisone 的促进作用。
T80191	His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA	Endogenous Metabolite	Metabolism
	His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA，GHRP-1的一种代谢产物，属于生长激素释放肽类。作为Ala-His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2的同义物，GHRP-1能够刺激GH（生长激素）的释放。在大鼠垂体静态单层细胞试验中，GHRP-1可提高GH释放率和[Ca2+]i水平，但对cAMP浓度无显著影响。
T78003	[D-p-Cl-Phe6,Leu17]-VIP TFA
	[D-p-Cl-Phe6,Leu17]-VIP TFA，为竞争性及选择性血管活性肠肽(VIP)受体拮抗剂，其IC50为125.8 nM。该化合物针对胰高血糖素、促胰液素和GRF受体均不表现活性。

化合物

Human growth hormone-releasing factor acetate

Cat.No: TP1155L

Target: GHSR

Human growth hormone-releasing factor

Cat.No: TP1155

Synonym: Growth Hormone Releasing Factor human

Cat.No: T82322

Synonym: Mouse growth hormone-releasing factor

Human growth hormone-releasing factor TFA

Cat.No: T75713

CJC-1295 acetate(863288-34-0 free base)

Cat.No: TP2328L

Synonym: DAC:GRF acetate

Target: GHSR

Cortistatin-8 acetate

Cat.No: TP2236L

Synonym: Cortistatin-8 acetate(485803-62-1 Free base)

Target: GHSR

Cat.No: T34281

Synonym: BIM28131,RM 131,BIM-28131,BIM-28163,BIM 28163,BIM28163,BIM 28131

Target: GHSR

Ipamorelin 2 Pivalic acid

Cat.No: T7809L

Synonym: NNC-26-0161

Target: Others

Cat.No: T3630

Synonym: RVT-601,瑞卢戈利,TAK-385

Target: GNRH Receptor

Cat.No: TP1570

Target: Somatostatin

Pralmorelin HCl

Cat.No: T5025L2

Synonym: WAY-GPA 748,WAY-GPA-748 WAY-GPA748,Pralmorelin dihydrochloride

[His1,Nle27] GHRF (1-32), amide, human

Cat.No: T76317

Somatorelin (1-44) amide (human) (trifluoroacetate salt)

Cat.No: T36377

Cat.No: T76318

Cat.No: T7809

Synonym: 伊帕瑞林,NNC-26-0161

Target: Others

(D-Ala2)-GRF (1-29) amide (human)

Cat.No: T83549

a-Helical Corticotropin Releasing Factor (9-41)

Cat.No: T76204

sGnRH-A acetate

Cat.No: T76312L

Cat.No: T76312

Acetyl-(D-Arg2)-GRF (1-29) amide (human)

Cat.No: T78039

Cat.No: T82000

Cat.No: T78023

Cat.No: T76325

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA

Cat.No: T80191

Target: Endogenous Metabolite

[D-p-Cl-Phe6,Leu17]-VIP TFA

Cat.No: T78003

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00186	GHRH Protein, Human, Recombinant (hFc) GRF,INN,growth hormone releas...	Human	HEK293 Cells
	The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl...
TMPJ-00365	GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated AXLLG,Growth arrest-specific protein 6,AXL receptor...	Human	HEK293 Cells
	Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, plat...
TMPJ-00366	GAS6 Protein, Human, Recombinant (hFc) AXLLG,Gas6,GAS-6,AXLLGAXL stimulatory factor,growth...	Human	HEK293 Cells
	GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ...
TMPY-04999	GAS6 Protein, Human, Recombinant (His)	Human	HEK293
	GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ...

重组蛋白

GHRH Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00186

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00365

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00366

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Human, Recombinant (His)

Cat.No: TMPY-04999

Species: Human

Expression System: HEK293

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